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Dr. Jennifer Arnold and husband Bill Klein both have achondroplasia, a bone-growth disorder that causes dwarfism. They are stars of the reality show "The Little Couple" - Jennifer is a neonatalogist who works at the Texas Children's Hospital (she did her residency at Children's Hospital of Pittsburgh, where most patients older than 4 are taller than she is) and Bill is a businessman. 

 The show features their efforts to build a house that is customized for their size, start a new business, and have a child. 

 Achondroplasia is caused by an autosomal dominant allele and individuals who inherit two copies of the allele do not survive to birth. 

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